Most enterprise AI programs are failing quietly — not because the technology underperforms, but because organizations layer tools onto legacy workflows instead of pursuing genuine end-to-end process transformation. For CEOs, the path to competitive differentiation requires personally owning the rewiring agenda, prioritizing the three to five mission-critical processes that deliver disproportionate value, and building the governance architecture to make transformation compound. This guide delivers the frameworks senior leaders need to architect enterprise rewiring that sticks.